Urine-based Test Shows Promise in Detecting Bladder Cancer

TOPLINE: A urinary DNA methylation test demonstrated high sensitivity and specificity for detecting high-grade or invasive bladder cancer, outperforming both nuclear matrix protein 22 (NMP22) and urine cytology tests in sensitivity. However, the new test’s positive predictive value is suboptimal, indicating limitations in confirming the presence of high-grade or invasive bladder cancer…