Novel Neutrophil Subset Predicts Relapse in ANCA Vasculitis

TOPLINE: Researchers in Japan showed that a unique neutrophil subset, characterized by type II interferon signature genes (T2ISG), along with elevated levels of interferon gamma in the blood, can predict the risk for relapse in patients with new-onset microscopic polyangiitis (MPA). METHODOLOGY: Researchers conducted single-cell transcriptome and surface proteome analyses of peripheral white blood cells …